王迎伟教授课题组
  1. Lisha Liu, Wen Qiu, Hui Wang, Yan Li, Jianbo Zhou, Mei Xia, Kai Shan, Rongrong Pang, Ying Zhou, Dan Zhao, Yingwei Wang*. Sublytic C5b-9 complexes induce the apoptosis of glomerular mesangial cells in rats with Thy-1 nephritis through role of interferon regulatory factor-1-dependent caspase 8 activation. J Biol Chem 2012;287:16410-16423 (IF =5.386 )
  2. Wen Qiu, Yan Zhang, Xiaomei Liu, Jianbo Zhou, Yan Li, Ying Zhou, Kai Shan, Mei Xia, Nan Che, Xuefeng Feng, Dan Zhao and Yingwei Wang*. Sublytic C5b-9 complexes induce proliferative changes of glomerular mesangial cells in rat Thy-1 nephritis through TRAF6-mediated PI3K-dependent Akt1 activation. J Pathol 2012; 226: 619-632. (IF = 7.274)
  3. Kuanfeng Xu,Ying Zhou, Wen Qiu,Xin Liu,Mei Xia,Lisha Liu,Xiaomei Liu,Dan Zhao,Yingwei Wang.Activating transcription factor 3 (ATF3) promotes sublytic C5b-9-induced glomerular mesangial cells apoptosis through up-regulation of Gadd45 and KLF6 gene expression. Immunobiology 216 (2011) 871–881
  4. Xiaoming Jiang, Jing Zhang, Xia Mei, Wen Qiu, Dan Zhao, Yingwei Wang. Role of activating transcription factor 3 (ATF3) in sublytic C5b-9-induced glomerular mesangial cell apoptosis. Cell Mol Immunol, 2010，7，143-151（(corresponding author，SCI，IF=2.765)
  5. Qiu W, Che N, Feng X, Xia M, Wang H, Zhao D, Wang Y. Apoptosis of glomerular mesangial cells induced by sublytic C5b-9 complexes in rats with Thy-1 nephritis is dependent on Gadd45 gamma upregulation. Eur J Immunol2009, 39(11): 3251-3266 (IF=5.179)
  6. L. Gao, Y. Zhang , W. Qiu, W. Xu, X. Feng,J. Ren, X. Jiang, H. Wang, D. Zhao, Y. Wang * . Effects of PI3-k/Akt shRNA on proliferation, fibronectin (FN) production and synthesis of Tsp-1 and TGF-β1 in glomerular mesangial cells (GMCs) induced by sublytic C5b-9 complexes. Cell prolif. 2009, 42,83-93 (corresponding author，SCI，IF=3.12)
  7. Juan Xu, Wenhuan Xu, Xia Chen, Dan Zhao, Yingwei Wang* . Recombinant DNA vaccine of the early secreted antigen ESAT-6 by mycobacterium tuberculosis and Flt3 ligand enhanced the cell-mediated immunity in mice. Vaccine, 2008,26:4519-4525. (corresponding author，SCI，IF=3.37)
  8. H. Wang1,X.M. Jiang1, J.H. Xu2, J. Xu1, J. X. Tong, Y. W. Wang1,* The profile of gene expression and role of NF-κB on glomerular injury in rats with Thy-1 nephritis. Clin Exp Immunol, 2008, 152(3): 559-567. (corresponding author，SCI，IF=2.7)
  9. Gao L, Qiu W, Wang Y, Xu W, Xu J, Tong J. Sublytic complement C5b-9 complexes induce thrombospondin-1 production in rat glomerular mesangial cells via PI3-k/Akt: association with activation of latent transforming growth factor-beta 1 (abstract). Molecular Immunology, 2007,174.
  10. Gao L, Qiu W, Wang Y, Xu W, Xu J, Tong J. Sublytic complement C5b-9 complexes
    induce thrombospondin-1 production in rat glomerular mesangial cells via PI3-k/Akt: association with activation of latent transforming growth factor-beta 1. Clin Exp Immunol, 2006, 144(2): 326-334. (corresponding author，SCI，IF=2.7)
  11. Xu J, Qiu W, Wang Y, Xu J, Tong J, Gao L, Xu W, Wu Y. The gene expression profile and overexpression of apoptosis-related genes (NGFI-B and Gadd 45 g ) in early phase of Thy-1 nephritis model. Cell Tissue Res, 2006, 326 (1): 159-168. (corresponding author, SCI, IF=2.5)
  12. Wang Y, He Q, Qin H, Xu J, Tong J, Gao L, Xu J. The complement C5b-9 complexes induced injury of glomerular mesangial cells in rats with Thy-1 nephritis by increasing nitric oxide synthesis. Life Sci, 2006, 79: 182-192. ( corresponding author, SCI, IF=2.3)
  13. Wang Y, Tong J Tang R, Dong H, Xu J. Inhibitory effects of ligustrazine, a modulator of thromboxane-prostacycline-nitric oxide balance, on renal injury in rats with passive Heymann nephritis. Nephron Physiology, 2004, 98: 80-88.
  14. Wang Y, He Q, Qin H,Gao F, Tang R. The study on synthesis of nitric oxide mediated by human membranous-bound complement C5b-9 complexes in rat glomerular mesangial cells. U. S. Chinese Journal of Microbiology and Immunology, 2002, 4 (1): 61-67